Research overview: canine distemper virus emergence and morbillivirus phylogeny across large carnivores
Canine distemper virus (CDV) is a morbillivirus closely related to measles and rinderpest that has expanded its host range far beyond dogs to infect lions, tigers, leopards, hyenas, seals and many other carnivores. This overview surveys how CDV strains are classified into geographic lineages, how the virus binds host receptors (notably SLAM and nectin-4), and why receptor adaptation may underlie spillover into felids. It synthesizes research on cross-species jumps, the role of multi-host communities in maintaining transmission, and the conservation alarm raised by die-offs in Serengeti lions and Amur tigers. The aim is to give enthusiasts a grounded picture of why a dog-associated virus repeatedly devastates wild cat populations and how phylogenetics helps trace outbreak origins.
Category:disease-epidemiology
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