🧬 The Felid Wiki — 3,000 research summaries

This influential study used feline immunodeficiency virus as a fast-evolving genetic marker to reconstruct the population history of its puma hosts in the American West. Because the virus mutates far…

R. Biek, A. J. Drummond, M. Poss · Science · 2006

This study described a feline leukemia virus (FeLV) outbreak in the endangered Florida panther, a small, inbred puma population. Through surveillance testing, the authors detected progressive FeLV inf…

M. W. Cunningham, M. A. Brown, D. B. Shindle, et al. · Journal of Wildlife Diseases · 2008

This study documented the first confirmed natural SARS-CoV-2 infections in big cats, occurring in tigers and lions at the Bronx Zoo early in the COVID-19 pandemic. After several cats developed respira…

D. McAloose, M. Laverack, L. Wang, et al. · mBio · 2020

Challenging the assumption that FIV is harmless in its natural hosts, this study examined wild African lions for clinical and pathological signs associated with feline immunodeficiency virus infection…

M. E. Roelke, J. Pecon-Slattery, S. Taylor, et al. · Virology · 2009

Captive cheetahs suffer unusually high rates of chronic gastritis associated with Helicobacter infection, a condition far more severe than in most other felids and a significant cause of morbidity in…

Hepatozoon is a tick-associated protozoan parasite, transmitted not by tick bite but by ingestion of infected ticks, that commonly infects wild felids including lions. This overview surveys the biolog…

Many of the most important felid diseases, from distemper to leukemia virus to Toxoplasma, originate at the interface of domestic animals, wildlife and people, making them quintessential One Health pr…

Following the Bronx Zoo tigers, SARS-CoV-2 infections were confirmed in big cats at zoos and sanctuaries across multiple countries, including additional tigers, lions, snow leopards, pumas and others.…

Sarcocystis parasites cycle between predator definitive hosts and prey intermediate hosts, with felids shedding infective stages after eating cysts in muscle. This overview surveys the role of wild ca…

Spirometra tapeworms use felids and other carnivores as definitive hosts, while their larval stages, known as spargana, infect a wide range of intermediate and paratenic hosts, including amphibians, r…

Toxocara cati and related ascarid roundworms are among the most common parasites of cats, with wild felids shedding eggs that contribute to environmental contamination and pose a zoonotic risk to peop…

Research into how Toxoplasma alters host behavior has implicated changes in neurotransmitter and hormone systems, particularly dopamine and testosterone. This overview surveys findings that the parasi…

Serosurveys consistently reveal high Toxoplasma exposure in wild felids, reflecting their role as both definitive hosts and predators of infected prey. This overview synthesizes prevalence patterns ac…

African lions and other wild felids can be infected with Trypanosoma, tsetse-transmitted protozoan parasites better known for causing sleeping sickness in humans and nagana in livestock. This overview…

Sylvatic plague, caused by the bacterium Yersinia pestis, circulates among rodents in the American West, and mountain lions become exposed by preying on infected rodents and lagomorphs. This overview…

Anthrax, caused by the spore-forming bacterium Bacillus anthracis, periodically kills wildlife in African ecosystems, and lions and other scavenging felids become exposed by feeding on infected herbiv…

Some Toxoplasma infections in southern sea otters involve unusual atypical genotypes, including a so-called Type X strain rarely seen in domestic cats. This overview surveys research suggesting that w…

Babesia are tick-transmitted protozoa that infect red blood cells and can cause anemia, and they have featured prominently in felid disease, most dramatically in the drought-linked mortality of Sereng…

African carnivores, including lions, leopards and cheetahs, host a rich diversity of blood-borne parasites that molecular surveys continue to uncover. This overview surveys the diversity of hemoparasi…

In ecosystems like Kruger, African buffalo serve as the maintenance host for bovine tuberculosis, and lions acquire infection chiefly by feeding on diseased buffalo. This overview surveys the transmis…

Canine distemper virus (CDV) is a morbillivirus closely related to measles and rinderpest that has expanded its host range far beyond dogs to infect lions, tigers, leopards, hyenas, seals and many oth…

Long-term studies that radio-collar wild felids provide rare opportunities to determine causes of death, including disease, with precision. This overview surveys how telemetry-based monitoring quantif…

Climate change is reshaping the distribution and intensity of wildlife disease, with implications for felids through effects on vectors, reservoirs and host stress. This overview surveys how warming a…

Felids are relatively susceptible to Yersinia pestis, and infection can progress to acute, severe and sometimes fatal disease, distinguishing cats from more resistant carnivores. This overview surveys…

Although cats are the definitive host, felids can also suffer clinical toxoplasmosis, particularly when immunocompromised or exposed to virulent strains. This overview surveys reports of disease in ca…

Wild felids rarely carry a single pathogen, and interactions among co-infecting agents can determine whether infection is benign or deadly. This overview surveys the concept of co-infection synergy in…

Understanding why some felids tolerate pathogens that sicken others requires comparing immune function across wild and domestic cats. This overview surveys comparative felid immunology, examining diff…

Feline immunodeficiency virus causes an AIDS-like syndrome in domestic cats yet has long been assumed benign in its wild hosts. This overview examines the evidence for and against that assumption, com…

The COVID-19 pandemic revealed a web of animal infections, with cats among the susceptible species alongside mink, ferrets and others. This overview surveys cross-species SARS-CoV-2 dynamics relevant…

Demodex mites live in the skin of many mammals, usually harmlessly, but can proliferate to cause demodectic mange when host immunity falters. This overview surveys reports of demodicosis in wild and c…